EXOSOMES DERIVED FROM M2 MACROPHAGES PREVENT STEROID-INDUCED OSTEONECROSIS OF THE FEMORAL HEAD BY MODULATING INFLAMMATION, PROMOTING BONE FORMATION AND INHIBITING BONE RESORPTION

Abstract Inflammatory reactions are involved in the development of steroid-induced osteonecrosis of the femoral head(ONFH).Studies have explored the therapeutic efficacy of inhibiting inflammatory reactions in steroid-induced ONFH and revealed that inhibiting inflammation may be a new STEVIA strategy for preventing the development of steroid-induce

Background The effectiveness of the currently available box jellyfish (Chironex fleckeri) antivenom has been subject of debate for many years.To assess whether the box jellyfish antivenom has the ability to attenuate venom-induced damage at cellular level, the present study analyzed the dose and time dependence of the antivenom in a cell-based assa

The study of deoxyribonucleic acid (DNA) is crucial in many fields, including medicine, biology, zoology, agriculture, and forensics.Since reading a DNA sequence is onerous because of its massive length, it is common in many DNA analysis applications to divide DNA strands into small segments or fragments which, after analysis, must be reassembled.S

The aim of this note is to deduce error estimates for a fully-discrete finite element method approximation of a kind of degenerate mixed parabolic equations.The obtained results consider regularity assumptions about the main variable according to Work and Harness Leather Headstalls the degenerate character of the problem, given by the term involvin